Handbook of drug screening /
| Diğer Yazarlar: | , |
|---|---|
| Materyal Türü: | Kitap |
| Dil: | English |
| Baskı/Yayın Bilgisi: |
New York :
Marcel Dekker,
c2001.
|
| Seri Bilgileri: | Drugs and the pharmaceutical sciences ; 114
|
| Konular: | |
| Online Erişim: | Table of Contents |
İçindekiler:
- Moving into the third millennium after a century of screening
- Basic considerations in designing high-throughput screening assays
- Screening platforms
- Homogeneous assays for high-throughput and ultrahigh-throughput screening
- Microbe-based screening systems
- Molecular genetic screen design for agricultural and pharmaceutical product discovery
- Receptor screens for small molecule agonist and antagonist discovery
- Functional assay screens
- Enzyme screens
- Screening strategies for ion channel targets
- High-throughput screening assays for detection of transcription
- Screening of combinatorial biology libraries for natural products discovery
- Higher-throughput screening assays with human hepatocytes for hepatotoxicity, metabolic stability, and drug-drug interaction potential
- High-throughput screening for metabolism-based drug-drug interactions
- The ATCG of drug discovery
- Genomics/functional proteomics for identification of new targets
- Bioinformatics: identification of novel targets and their characterization
- The evolution of laboratory automation
- Robotics and automation
- Assay miniaturization: developing technologies and assay formats
- Screening in the NanoWorld: single-molecule spectroscopy and miniaturized high-throughput screening.